專技 - 調劑學與臨床藥學題庫下載題庫

有人知道為啥C不能選嗎

低血鉀、低血鎂及高血鈣會加強digoxin的藥效反應，甚至導致中毒現象

我就選了個保鉀..

Interactions between your drugs

Minordigoxin

spironolactone

Applies to: digoxin, spironolactone

Spironolactone may reduce the tubular secretion of digoxin. Plasma clearance of digoxin may be decreased, and plasma levels may increase. Also, limited data indicate that spironolactone may have a negative inotropic side effect. Finally, spironolactone may interfere with some digoxin radioimmunoassays, and digoxin concentrations may be overestimated. During coadministration...

查看完整內容

有人知道為啥C不能選嗎

低血鉀、低血鎂及高血鈣會加強digoxin的藥效反應，甚至導致中毒現象

我就選了個保鉀..

Interactions between your drugs

Spironolactone may reduce the tubular secretion of digoxin. Plasma clearance of digoxin may be decreased, and plasma levels may increase. Also, limited data indicate that spironolactone may have a negative inotropic side effect. Finally, spironolactone may interfere with some digoxin radioimmunoassays, and digoxin concentrations may be overestimated. During coadministration, the patient should be monitored for signs and symptoms of digoxin toxicity, levels should be checked when necessary, and the clinician should keep in mind the possibility that digoxin levels may falsely appear to be elevated. Patients should be advised to notify their physician if they experience nausea, anorexia, visual changes, or irregular heartbeats.