試題詳解

45. In a number of species calorie restriction without malnutrition may slow the biological aging process, resulting in longer maintenance of youthful health and an increase in both median and maximum lifespan. Which of the followings is   not   involved in the underlying mechanism?
(A) Reduced levels of insulin and IGF-1.
(B) Increased gluconeogenesis.
(C) Activation of AMPK.
(D) Reduced production of reactive oxygen species.
(E) Activation of Sirt-1.