46. 補體系統於先天性免疫反應中對於入侵的細菌有很大的防禦作用,其中補體系統對於直接攻擊細菌,會形成攻膜複合物(Membrane-attack complex),下列何種補體蛋白不是組成攻膜複合物的蛋白?
(A) C3
(B) C9
(C) C6
(D) C8
答案:登入後查看
統計: A(402), B(73), C(57), D(78), E(0) #3098422
統計: A(402), B(73), C(57), D(78), E(0) #3098422
詳解 (共 7 筆)
#7207417
31. 會在入侵細菌的細胞膜上穿孔的是:
(A) 巨細胞
(B) T細胞
(C) 補體
(D) 蓍中性球
答案:C
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30. 有關補體系統(complement system)的敘述,下列何者最正確?
(A) 一組參與後天性免疫的蛋白質。
(B) 一組由細胞毒性 T 細胞分泌的蛋白質
(C) 一組包括干擾素和介白素(interleukin)的蛋白質
(D) 一組以級聯(cascade)方式共同作用的抗菌蛋白
答案:D
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52. Which one of the following statement about the immune system is correct?
(A) The innate immunity is found in all animals and plants.
(B) The adaptive immune response is activated before the innate response and develops quickly.
(C) The helper T cells recognize peptide antigens in major histocompatibility complex MHC class I molecules on dendritic cells.
(D) Perforin triggers blood vessels to dilate and become more permeable.
(E) The complement system provides innate defense by interfering with viruses and helping activate macrophages.
答案:A
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49. Which description about complement system is incorrect?
(A) requires antibody to target pathogen
(B) can attract phagocytic leukocyte
(C) normal body cells continuously produce proteins that inactivate complement
(D) activation of one complement protein can trigger the enzymatic cleavage of anotiier complement protein
(E) is part of the innate immunity system
答案:A
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60. Through which of the following mechanisms is IgG most likely to contribute to the activation of the complement system?
(A) Cooperate with TLR3 (Toll-like receptor 3) to modulate the formation of C5b.
(B) Facilitate the initiation of the complement cascade through Fc region binding to C1 protein.
(C) Interact with CD4 to modulate the release of IL-10.
(D) Deliver viral antigens to the thymus as part of negative selection.
(E) Indirectly regulate complement activity by inhibiting the release of perforin and granzymes.
答案:B
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7. 補體系統(complement system)中,扮演煞車角色的補體調控蛋白質如 decay-accelerating factor (DAF)等,會辨認並降解補體中的何種成員?
(A) C1b
(B) C3b
(C) C5b
(D) C9
答案:B
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12. 在人類先天性免疫反應中有所謂補體系統,其發生反應時需有很多酵素反應,下列何種組合全是 C5 轉換酶(C5 convertase),讓補體可以形成攻膜複合物,進而殺死細菌?
I:C4b2a3b II:C3bBb III:C3b2Bb IV:C4b2a
(A) I、II
(B) II、III
(C) II、IV
(D) I、III
答案:D
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#6154021
有多種蛋白質參與膜攻擊複合物的組裝。具有高活性的C5b會與C6連接形成C5b-6複合體,隨後,C5b還會與C7連接形成C5b-6-7複合體。C5b-6-7複合物又會與由α、β、γ三條鍊構成的C8結合,形成C5b-6-7-8配合體。後者又會與C9結合[2][3][4],並作為C9聚合的催化劑。
By 維基
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