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64 下列藥物中，何者在體內會產生 methyl carbonium ion，而作用於 DNA 上？
(A) Streptozocin
(B) Chlorozotocin
(C) Thiotepa
(D) Bleomycin

答案：登入後觀看
難度： 困難

	1F Bryan 國三上 (2014/05/26) Streptozotocin is a naturally occurring chemical that is particularly toxic to the insulin-producing beta cells of the pancreas in mammals. It is used in medicine for treating certain cancers of the Islets of Langerhans and used in medical research to produce an animal model for Type 1 diabetes in large dose as well as Type 2 diabetes with multiple low doses. 檢舉
	2F Bryan 國三上 (2014/05/26) 胰臟胰島細胞癌，用Streptozocin治療較為有效，且少有骨髓之毒性檢舉
	3F Bryan 國三上 (2014/05/26) Streptozocin 產生methyl carbonium ion烷化單股DNA及抑制新的DNA合成檢舉

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專技 - 藥理學與藥物化學題庫下載題庫