48. Which one of the following statement about central pain is wrong?
(A) Central pain involves plasticity in a single area of CNS.
(B)Sensitization of the CNS plays a major role in central pain and involves neuronal
hyper-excitability resulting in an increased response to synaptic inputs, decreased threshold,
expansion of receptive fields, and access of low-threshold Aβ mechanoreceptors to pain
pathways.
(C) The clinical consequences of central pain are allodynia, hyperalgesia, and after-sensations.
(D) Central sensitization may also include spontaneous discharges.
(E) Spontaneous discharges in damaged pain pathways or deafferented rostral neurons may be
responsible for spontaneous ongoing or intermittent pain.