試題詳解

5. In the thymus, a T cell with both CD4 and CD8 receptors (double-positive thymocyte) interacts with a self-peptide presented by a self-MHC class I molecule. If the binding affinity between the T cell receptor and the self-peptide: MHC complex is low, what is the outcome?
(A) Negative selection and apoptosis
(B) Cell activation
(C) Rearrangement of the second β-chain locus
(D) Positive selection of a CD4 T cell
(E) Positive selection of a CD8 T cell