51.有關肌紅素尿腎病(myoglobinuric nephrosis),何者錯誤?
(A)與肌肉溶解性疾病有關
(B)因肌紅素對腎小管上皮具直接細胞毒性所致
(C)鏡下可見大量肌紅素圓柱體堆積於腎小管腔中
(D)鏡下病變不易和血紅素尿腎病(hemoglobinuric nephrosis)區分
答案:登入後查看
統計: A(14), B(1450), C(326), D(252), E(0) #2970875
統計: A(14), B(1450), C(326), D(252), E(0) #2970875
詳解 (共 5 筆)
#6543535
尋求高人指教:
Myoglobin 本身到底對腎小管有沒有毒性?
Myoglobin 本身到底對腎小管有沒有毒性?

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Myoglobin contains iron as ferrous oxide, which is necessary for binding with oxygen. The oxidation of ferrous oxide to ferric oxide generates free hydroxyl radicals that can injure tubular epithelium and cause nephrotoxicity. Myoglobin itself can exhibit peroxidase-like enzyme activity and leads to lipid peroxidation. Therefore, a direct toxic effect of the myoglobin on the renal tubules...(no access 閱讀全文QQ)
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