53.下列何者為抗甲狀腺機能亢進藥物perchlorate主要的作用機轉?
(A)阻斷甲狀腺攝取碘離子(thyroidal uptake of iodide)的作用
(B)抑制甲狀腺過氧化物酶催化反應(thyroid peroxidase-catalytic reaction)
(C)其促進周邊將triiodothyronine(T3)及 tetraiodothyronine(T4)進行脫碘化作用(deiodination)
(D)其具有抑制碘有機化(iodine organification)及減少triiodothyronine(T3)及 tetraiodothyronine(T4)釋放
的作用
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統計: A(291), B(71), C(59), D(107), E(0) #1634559
統計: A(291), B(71), C(59), D(107), E(0) #1634559
詳解 (共 4 筆)
#5396131
競爭Na+/I- Symporter 機轉:阻斷攝取碘離子:ClO4-
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#3099369
Potassium perchlorate has, in the past, been used therapeutically to treat hyperthyroidism resulting from Graves' disease. It impedes the accumulation of iodide in the thyroid, which blocks thyroid hormone production
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