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34.治療癲癇之藥物Lamotrigine與下列那一種藥物合併使用時，Lamotrigine的體內代謝半衰期可以被延長？
(A)Valproic acid
(B)Topiramate
(C)Tiagabine
(D)Phenytoin

藥理學- 103 年 - 103-1 專技高考_藥師：藥理學與藥物化學#14226

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最佳解!
	小羊國二下 (2015/06/19) Valproic acid為C.....觀看完整全文，請先登入檢舉

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	9F 孟大二下 (2021/05/30) 66 治療癲癇之藥物 lamotrigine 與下列那一種藥物合併使用時，lamotrigine 的體內代謝半衰期可以被延長？ (A) Topiramate (B) Phenytoin (C) Valproic acid (D) Tiagabine 編輯私有筆記及自訂標籤醫學二：100題 ( 包括生理學,生化學,藥理學,病理學等科目及其臨床相關知識 )- 99 年 - 99-2 專技高考_醫師(一)：醫學（二）（包括生理學、生化學、藥理學、病理學等科目及其臨床相關知識）#47170 答案：C 難度：適中統計： A(0),B(3),C(10),D(3),E(0) #1215527 個人：尚未作答檢舉
	10F 大威天龍 (2024/04/20) Lamotrigine交互作用 1.valproic acid: Serious adverse events related to AED hypersensitivity syndrome may be seen, especially when coadministered with valproic acid. The development of myoclonus after 2-3 years of treatment has also been reported.73 Other common side effects include somnolence, headache, dizziness, diplopia, ataxia, and nausea. Concomitantly administered AEDs that induce UGT enzymes cause a significant decrease in blood plasma levels of lamotrigine. Valproate significantly reduces lamotrigine clearance by inhibiting UGT; thus, the dose of lamotrigine should be reduced to avoid ... 查看完整內容 Lamotrigine交互作用 1.valproic acid: Serious adverse events related to AED hypersensitivity syndrome may be seen, especially when coadministered with valproic acid. The development of myoclonus after 2-3 years of treatment has also been reported.73 Other common side effects include somnolence, headache, dizziness, diplopia, ataxia, and nausea. Concomitantly administered AEDs that induce UGT enzymes cause a significant decrease in blood plasma levels of lamotrigine. Valproate significantly reduces lamotrigine clearance by inhibiting UGT; thus, the dose of lamotrigine should be reduced to avoid toxici- ties. 2.oral contraceptive ethinylestradiol 檢舉
	11F 大威天龍 (2024/04/20) Valproic acid交互作用檢舉

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