55.下列何者可經口、局部、靜脈投藥用於治療herpes simplex感染？
(A)rimantadine
(B)ganciclovir
(C)acyclovir
(D)amantadine

Ganciclovir is also a nucleoside analog but is more potent than acyclovir against herpesviruses, including FHV-1, EHV-1, and human cytomegalovirus (Maggs and Clarke, 2004).

Ganciclovir is administered systemically as an injectable formulation for intravenous administration or as an oral tablet.

Similar to acyclovir and penciclovir, ganciclovir is poorly absorbed after oral administration, so it has also been formulated as a valine ester prodrug to enhance oral absorption. 

nGanciclovir is a first-line therapeutic agent for cytomegalovirus infections in people, since acyclovir and penciclovir are less potent and less efficacious against these viruses.

Ganciclovir is similarly potent when tested in vitro against several herpesviruses of veterinary importance, including the zoonotic, Monkey B virus, endemic to macaques (獼猴) (Brush et al., 2014).

Ganciclovir has also been administered intravenously to horses at later stages of infection with EHV-1, when valacyclovir administration may be ineffective (Maxwell et al., 2011).  

Reference: Veterinary Pharmacology and Therapeutics, 10th Edition