55.在平滑肌收縮過程中，Ca2+與下列何者結合後才能促使cross-bridge cycling進行，並啟動收縮？
(A)actin
(B)myosin
(C)troponin
(D)calmodulin

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統計： A(9), B(25), C(140), D(471), E(0) #1844831

詳解 (共 2 筆)

#4994170
橫紋肌中結合troponin C平滑肌中...
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平滑肌

Calmodulin plays an important role in excitation contraction (EC) coupling and the initiation of the cross-bridge cycling in smooth muscle, ultimately causing smooth muscle contraction.  The free calcium binds to a special calcium binding protein called calmodulin.  Calcium-calmodulin activates myosin light chain kinase (MLCK), an enzyme that is capable of phosphorylating myosin light chains (MLC) in the presence of ATP.  Myosin light chains are 20-kD regulatory subunits found on the myosin heads. MLC phosphorylation leads to cross-bridge formation between the myosin heads and the actin filaments, and hence, smooth muscle contraction.

骨骼肌

The binding of calcium ions to troponin C triggers vertebrate striated (skeletal or cardiac) muscle contraction

Source : google search

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