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https://en.wikipedia.org/wiki/Multiple_electrode_aggregometry

RISTOtest can be performed in two concentrations; RISTOhigh and RISTOlow. In RISTOhigh, a ristocetin concentration of 0,77 mg/ml is applied. This normally induces a strong platelet aggregation, and low or absent aggregation can be caused by the earlier mentioned conditions vWD and BSS.^[13] In RISTOlow, the ristocetin concentration is just 0,2 mg/ml, and at a level that does not normally induce a strong aggregation response. This test can detect if vWF shows a stronger than normal tendency to aggregate platelets, which can be s...

https://en.wikipedia.org/wiki/Multiple_electrode_aggregometry

RISTOtest can be performed in two concentrations; RISTOhigh and RISTOlow. In RISTOhigh, a ristocetin concentration of 0,77 mg/ml is applied. This normally induces a strong platelet aggregation, and low or absent aggregation can be caused by the earlier mentioned conditions vWD and BSS.^[13] In RISTOlow, the ristocetin concentration is just 0,2 mg/ml, and at a level that does not normally induce a strong aggregation response. This test can detect if vWF shows a stronger than normal tendency to aggregate platelets, which can be seen in a subtype of vWD called vWDIIb