63.臨床上使用paclitaxel於腫瘤之化學治療,下列何種因素不是治療失敗之..-阿摩線上測驗
2F ning 大一上 (2017/02/12)
steroid xenobiotic receptor The steroid and xenobiotic receptor (SXR) (also known as pregnane X receptor or PXR) is a nuclear hormone receptor activated by a diverse array of endogenous hormones, dietary steroids, pharmaceutical agents, and xenobiotic compounds. SXR has an enlarged, flexible, hydrophobic ligand binding domain (LBD) which is remarkably divergent across mammalian species and SXR exhibits considerable differences in its pharmacology among mammals. The broad response profile of SXR has led to the development of "the steroid and xenobiotic sensor hypothesis". SXR has been est... 查看完整內容 |
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