65 Azathioprine 與 allopurinol 的藥品交互作用之成因係共用下列何種酵素？
(A) Hypoxantine-guanine phosphoribosyltransferase（HGPRT）
(B) Xanthine oxidase
(C) Phophoribosyl-1 pyrophosphate（PRPP）synthetase
(D) Cytochrome P 450 3A4

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統計： A(54), B(1360), C(8), D(24), E(0) #415027

詳解 (共 2 筆)

#5488314
The concomitant administration of allopurinol and azathioprine or mercaptopurine requires a dose reduction to one-third to one-fourth of the usual dose of the thiopurine because concomitant administration could increase plasma concentrations of these thiopurines, resulting in severe toxicity.
reference: uptodate
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#6491517
藥物 Azathioprine 交互作...
(共 121 字，隱藏中）
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