69.Ranolazine為一新穎抗心絞痛藥物,其作用機轉為何?
(A)抑制late component of the Na+ current
(B)活化rapid component of the delayed rectifier K+ current
(C)nitric oxide donor
(D)alpha-1 adrenergic receptor blocker
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統計: A(329), B(87), C(66), D(21), E(0) #1634575
統計: A(329), B(87), C(66), D(21), E(0) #1634575
詳解 (共 3 筆)
#2895452
Ranolazine is a newer antianginal drug that appears to act by reducing a late sodium current (I Na ) that facilitates calcium entry via the sodium-calcium exchanger (see Chapter 13). The resulting reduction in intracellular calcium concentration reduces cardiac contractility and work.
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