試題詳解

7. Which of the following statement concerning the cause of cancer pain is least likely?
(A) Vanilloid receptor TRPV1 is expressed in most nociceptors, it detects heat and extracellular protons.
(B) In order to detect noxious mechanical stimuli, nociceptors express mechanically gated channels that initiate a signally cascade upon excessive stretch.
(C) Low pH can activate acid-sensing ion channel-3 (ASIC-3).
(D) Tumour cells can release protons and produce local acidosis.
(E) TRPV1 is activated when the pH rise above 6.0.