阿摩線上測驗
70.李同學22歲，腎功能正常且無其他疾病。因綠膿桿菌引起之肺炎，欲以extended-interval dosing方式給與gentamicin。則適當的劑量應為多少mg/kg/day？
(A)10~12
(B)5~7
(C)2~4
(D)0.5~1
答案：登入後查看
統計： A(333), B(1986), C(293), D(172), E(0) #537461
統計： A(333), B(1986), C(293), D(172), E(0) #537461
詳解 (共 5 筆)
FiaYun
#1247797
Gentamicin
Usual dosage ranges IM, IV 4-7 mg/kg/dose once daily
Pneumonia, hospital- or ventilator-associated: IM, IV 7 mg/kg/day (with antipseudomonal beta-lactam or carbapenem)
57
0
沈花
#2899218
| MDD (multiple daily dosing) | OD (once daily) | |
Gentamicin Tobramycin | loading: 2 mg/kg then: 1.7 mg/kg q8h P 4-10 mcg/ml, T 1-2 mcg/ml | 5.1 (7 if critically ill) mg/kg P 16-24 mcg/ml, T<1 mcg/ml |
Amikacin Kanamycin Streptomycin | 7.5 mg/kg q12h P 15-30 mcg/ml, T 5-10 mcg/ml | 15 mg/ml/kg P 56-64 mcg/ml, T<1 mcg/ml |
Ref: 熱病2018 48th edition p.122表格
36
0
淨潔先生
#3430210
Usual dosage ranges:
Conventional: IM, IV: 3 to 5 mg/kg/day in divided doses every 8 hours
Once daily (extended-interval dosing [EID]): IV: 5 to 7 mg/kg/day once daily; not recommended in patients with ascites, burns covering >20% of the total body surface area, cystic fibrosis, end-stage renal disease (eg, requiring hemodialysis), endocarditis, infants, mycobacterial infections, or pregnancy (Bailey 1997; Nicolau 1995)
Reference Uptodate
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