75.王先生有長期飲酒習慣，對warfarin治療效果影響之敘述，下列何者正確？
(A)alcohol會增加warfarin之代謝
(B)alcohol會減少warfarin之代謝
(C)warfarin會加強酒精之鎮靜效果
(D)會產生disulfiram-like reaction

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統計： A(833), B(369), C(17), D(210), E(0) #416669

詳解 (共 4 筆)

#1108148
突然大量飲酒，會抑制代謝
長期飲酒，會促進代謝
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#2355751
長期飲酒，會促進代謝
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#5854620
warfarin與飲酒的交互作用需區別短...
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#2908501

Cirrhosis / regularly consume ethanol -> increased clearance of warfarin.

Social consumption of ethanol with food, in patients with normal hepatic function, does not appear to interfere with warfarin therapy

 

Micromedex DDI: warfarin & ethanol

Udall, 1970; O'Reilly, 1979; O'Reilly, 1981; Kater et al, 1969

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