8. 骨骼肌收縮時，肌漿網 (Sarcoplasmic reticulum) 中，何種離子會釋放至肌漿 (Sarcoplasm) 中？
(A) 鈣離子 (Ca²⁺)
(B) 鈉離子 (Na⁺)
(C) 鉀離子 (K⁺)
(D) 鎂離子 (Mg²⁺)
(E) 氯離子 (Cl⁻)

9. 口輪匝肌 (Orbicularis oris m.) 肌束屬於那一種的排列方式？(A) 平行 (Parallel)(B) 單側羽毛狀 (Unipennate)(C) 雙側羽毛狀 (Bipennate)(D) 環狀 (Circular)(E) 會聚式 (Convergent)

10. 下肢的淋巴液經淋巴管收集後，匯集至胸管 (Thoracic duct)，最後於何處注入血液中？ (A) 右鎖骨下靜脈 (Right subclavian v.) 和外頸靜脈 (External jugular v.) 會交處 (B) 右鎖骨下靜脈 (Right subclavian v.) 和內頸靜脈 (Internal jugular v.) 會交處 (C) 左鎖骨下靜脈 (Left subclavian v.) 和外頸靜脈 (External jugular v.) 會交處 (D) 左鎖骨下靜脈 (Left subclavian v.) 和內頸靜脈 (Internal jugular v.) 會交處 (E) 上腔靜脈 (Superior vena cava)

複選題1. If you want to use genetically engineered bacteria for the production of human growth hormone, you need the following ingredients. (A) A cDNA obtained by the reverse transcription of growth hormone mRNA (B) Endoproteinases (C) Genomic DNA of the growth hormone gene (D) A DNA sequence that codes for a bacterial ribosome-binding sequence (E) A bacterial promoter sequence

複選題2. The oncogenes of the human papillomavirus (A) Activate cyclin-dependent kinases by direct binding to the catalytic subunit (B) Bind and inactivate to the retinoblastoma (C) Bind to the host cell DNA, stimulating the transcription of antiapoptotic genes (D) Bind and inactivate to the p53 protein (E) Activate growth factor receptors in the absence of the normal ligand

複選題3. Select the sequences of the two 12-residue primers that could be used to amplify the following DNA segment by PCR. (A) ATAGCGATAGGC (B) GGCGTCGGTCAG (C) CTGACCGACGCC (D) TATCGCTATCCG (E) ATAGCGCTGACC

4. In order to compare the expression of a large number of genes in rhabdomyosarcoma cells with gene expression in normal skeletal muscle, you have isolated mRNA from the two sources by affinity chromatography on an oligi-dT column. The most common method to compare the two mRNA patterns would be (A) Expression cloning (B) In situ hybridization (C) cDNA microarrays (D) RNA interference (E) Nothern blotting

複選題5. Which statement(s) is suitable to describe antisense nucleic acids? (A) Can be used to silence a pathologic gene in patients. (B) Can be produced by an inverted gene. (C) Hybridize with DNA only but not with RNA. (D) Enhance the translation when bind to messenger RNA. (E) Can be used as probes to detect a stretch of DNA in the genome.

複選題6. Which statement(s) is suitable to describe ubiquitin? (A) An isopeptide bond forms between the C-terminus of ubiquitin and the e-amino group of the modified lysine residue. (B) Ubiquitination always leads the modified proteins to degradation. (C) ATP is required for activation of ubiquitin. (D) Multiple ubiquitin molecules can be covalently linked together to form a polyubiquitin chain on the modified protein. (E) The N-terminal amino acid of the modified protein is one determinant of its half-life.

複選題7. Which statement(s) is suitable to describe DNA replication? (A) 3' to 5' polymerase activity is used to synthesize both strands of DNA. (B) DNA replication is semiconservative. (C) A short strand of RNA is always used as the primer for DNA replication in all organisms. (D) Many specialized DNA polymerases exist to govern DNA replication in different situations. (E) Native DNA polymerases usually contain so called "proof-reading" exonuclease functions.

複選題8. Which statement(s) is suitable to describe transposons? (A) Transposons usually contain short inverted terminal repeat sequences. (B) Being named as retrotransposons if RNA intermediates are involved in the transposition. (C) Transposons can cause spread of antibiotic resistance within a bacteria population. (D) Only exist in metazoan genomes. (E) Transposase is not necessarily encoded in the transposon.

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