9 全身性麻醉劑若引發惡性高熱(Malignant hyperthermia)時，應以何種藥物治療？
(A) Ketorolac
(B) Dantrolene
(C) Acetaminophen
(D) Diazepam

答案：登入後查看
統計： A(2), B(275), C(25), D(1), E(0) #443674

詳解 (共 2 筆)

#812461

Definition of Malignant Hyperthermia:

Malignant hyperthermia is a group of inherited muscle problems characterized by muscle breakdown following certain stimuli -- such as anesthesia, extremes of exercise (particularly in hot conditions), fever, or use of stimulant drugs. The problems associated with this condition result from over-excitable muscles that contract uncontrollably, severe fever, abnormal heart rhythms, and kidney failure.

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#812464
Dantrolene sodium dissociates the excitation-contraction coupling, probably by interfering with the release of Ca++ from the sarcoplasmic reticulum. This effect appears to be more pronounced in fast muscle fibers as compared to slow ones, but generally affects both.
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