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研究所、轉學考(插大)◆生物化學
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112年 - 112 國立臺灣大學_碩士班招生考試：生物化學( C )#117435
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18. Please desctibe how the muscle glycogen phosphorylase is regulated by the enzymatic cascades of reversible phosphorylation in response to the stimulation of glucagon. (5%)
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13. The key enzyme in a metabolic pathway is usually regulated in many ways. For example, HMG-CoA reductase in the biosynthesis of cholesterol can be regulated in transcriptional levels or protein levels. Please describe these regulations in general. (10%)
#501717
14. Describe the details of the 4 general types of "signal transducers" (or receptors). The cellular locations of these transducers/receptors are related to the chemical nature, bydrophilic or hydrophobic, of the ligands or signals. Please discuss this issue. (10%)
#501718
15. Please draw the molecular structure of the pentapeptide "PNSKV" in the two- dimensional representation of Fisher projection. (5%)
#501719
17. Please select (pick out) the aspartic proteases and cysteine proteases, respectively, from the enzymes listed below. (5%) (A) Alanine aminopeptidase, (B) Pepsin, (C) Caspase 1, (D) Renin, (E) Elastase, (F) Thrombin, (G) Trypsin, (H) HIV-1 protease, (I) Carboxy peptidase A, (J) Papain
#501720
19. Biochemists use equilibrium dissociation constant Kp to describe the binding affinity of a protein to its ligand and use Michaelis constant Km to describe the binding affinity of an enzyme to its substrate. What are the definitions of Ko and Km, respectively? (5%)
#501722
22.Please discuss why the deficiency or dysfunction in amino acid and sugar m may affect the de novo biosynthesis of purines and pyrimidines? (10%)
#501723
1. 請說明高密度聚乙烯（HDPE）管之特性與用途？其施工要點為何？
#501724
2. 何謂錯接及漏水率？試問給水管線漏水發生的原因為何？目前自來水管網如何進行漏水檢測？
#501725
3. 試說明管線工程施工期間之作業有何相關規定？
#501726
4. 何謂水錘作用？並試說明如何防止？
#501727
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