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44 一位 52 歲急性肺炎患者住院治療,臥床 7 天後發生右下肢 proximal deep vein thrombosis,給予 heparin 併 warfarin 治療後略有改善。該患者出院後口服抗凝血劑 warfarin 至少應給多長? (A) 4 週 (B) 3 個月 (C) 6 個月 (D) 12 個月

45 一位罹患深部靜脈血栓已接受口服 warfarin 治療二個月的患者,INR(international normalized ratio) 正控制在理想的範圍時,若再合併使用下列何種藥物,可能會減弱 warfarin 的藥效? (A) Rifampin (B) Amiodarone (C) Cimetidine (D) Ketoconazole

56 一位工人由於大腿深部靜脈栓塞正在服用 warfarin,前凝血酵素時間(prothrombin time)INR (international normalization ratio)穩定控制在 2 左右。最近在工廠身體檢查時又發現得了肺結核, 已開始服用 rifampin。為了良好控制靜脈栓塞及避免併發出血,目前最適當的處理方式為何? (A)減低 warfarin 的劑量 (B)保持 warfarin 原來的劑量 (C)增加 warfarin 的劑量 (D)停止 warfarin,改用 aspirin

46. 如右圖所示,有一懸臂梁承受載重,其承受最大彎矩之斷面發生在何處? (A) A (B) B (C) C (D) D

17. The reaction of the citric acid cycle that is most similar to the pyruvate dehydrogenase complex-catalyzed conversion of pyruvate to acetyl-CoA is the conversion of: (A) citrate to isocitrate. (B) fumarate to malate. (C) malate to oxaloacetate. (D) succinyl-CoA to succinate. (E) -ketoglutarate to succinyl-CoA.

18. Which of the following statements apply (applies) to the oxidation of fatty acids? 1. The process takes place in the cytosol of mammalian cells.2. Carbon atoms are removed from the acyl chain one at a time.3. Before oxidation, fatty acids must be converted to their CoA derivatives.4. NADP+ is the electron acceptor.5. The products of oxidation can directly enter the citric acid cycle for further oxidation. (A) 1 and 3 only (B) 1, 2, and 3 (C) 1, 2, and 5 (D) 3 and 5 only (E) 4 only