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4. Eukaryotic RNA polymerase II required transcription factors for transcription. Which transcription factor can recognize a common promoter (TATA box)? Which transcription factor is responsible for phosphorylation on C-terminal domain of RNA polymerase II and what is the physiological meaning for such phosphorylation? (8%)
3. Why does liver damage cause jaundice? (5%)
2. High levels of cholesterol in the blood is positively correlated with the incidence of atherosclerosis. The ratio of LDL: HDL is a better indicator of coronary artery obstruction, Why? (6%)
Questions 22-25 refer to the following descriptions, list the characteristics that correctly describe that DNA repair process. (A) Damaged nucleotides are removed by nick translation (B) RecA protein participates (C) The repair system requires coenzyme FADH (D) Deficiency of this enzyme in humans greatly increases the risk of skin cancer (E) This process begins up to a kbp away from the site to be repaired
25. Mismatch repair_____
24. Recombinational repair_____
23. Base excision repair_____
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