王太太60歲，到急診之主訴為2天前開始在左臂下有麻痛與針刺的感覺，逐漸擴散到胸部..-阿摩線上測驗

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王太太60歲，到急診之主訴為2天前開始在左臂下有麻痛與針刺的感覺，逐漸擴散到胸部，今天在前述部位出現紅斑。她的免疫力與腎功能皆正常且沒有發燒、頭疼、視力模糊等症狀，過去病史包含在幼童時期曾經長水痘（chickenpox）
【題組】44.下列藥品治療方式何者正確？
(A)Acyclovir 800 mg PO q6h共7天
(B)Acyclovir 15 mg/kg IV q4h共7天
(C)Famciclovir 500 mg PO q4h共7天
(D)Valacyclovir 1000 mg PO tid共7天

專技 - 藥物治療學- 103 年 - 103-2 專技高考_藥師、藥師（二）：藥物治療學#17189

答案：D
難度： 困難

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	大仁Jason藥師國三下 (2015/05/14) 過去病史包含在幼童時期曾經長水痘（chi... (內容隱藏中) 查看隱藏文字

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	5F Amy Kuo 高一下 (2019/06/10) 健保規範: -帶狀疱疹發疹三日內(72小時內)且感染部位在頭頸部、生殖器周圍之病人，可給予五日內之口服或外用藥品 -使用 acyclovir 400mg 規格量口服錠劑除<骨髓移植術後病患預防性使用 acyclovir>外，療程以 7 天為限 (A)Acyclovir 800 mg PO 一天五次(約q4h) 共7天 Famciclovir (500 mg)及 Valacyclovir (1000 mg)的療效與 Acyclovir (800 mg) 差異不大，療程同是七天，但有較佳的生物利用率(bioavailability)，一天只需投藥三次檢舉
	6F 淨潔先生高三上 (2019/06/26) QID怎麼會是Q4H 檢舉
	7F 高分過大二下 (2020/07/21) Famciclovir : Five 500mg Acyclovir, the prototype antiviral drug, is a DNA polymerase inhibitor. Acyclovir may be given orally or intravenously. Major drawbacks of orally administered acyclovir include its lower bioavailability compared with other agents and its dosing frequency (five times daily). Intravenously administered acyclovir is generally used only in patients who are severely immunocompromised or who are unable to take medications orally. Valacyclovir, a prodrug of acyclovir, is administered three times daily. Compared with acyclovir, valacyclovir may be slightly better at decrea... 查看完整內容 Famciclovir : Five 500mg Acyclovir, the prototype antiviral drug, is a DNA polymerase inhibitor. Acyclovir may be given orally or intravenously. Major drawbacks of orally administered acyclovir include its lower bioavailability compared with other agents and its dosing frequency (five times daily). Intravenously administered acyclovir is generally used only in patients who are severely immunocompromised or who are unable to take medications orally. Valacyclovir, a prodrug of acyclovir, is administered three times daily. Compared with acyclovir, valacyclovir may be slightly better at decreasing the severity of pain associated with herpes zoster, as well as the duration of postherpetic neuralgia.Valacyclovir is also more bioavailable than acyclovir, and oral administration produces blood drug levels comparable to the intravenous administration of acyclovir. Famciclovir is also a DNA polymerase inhibitor. The advantages of famciclovir are its dosing schedule (three times daily), its longer intracellular half-life compared with acyclovir and its better bioavailability compared with acyclovir and valacyclovir. https://www.aafp.org/afp/2000/0415/p2437.html 檢舉

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王太太60歲，到急診之主訴為2天前開始在左臂下有麻痛與針刺的感覺，逐漸擴散到胸部..-阿摩線上測驗

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