複選題

1. Regarding to telomerase which statements is (are) CORRECT?
(A) It contains an RNA
(B) It contains a DNA
(C) It contains a protein
(D) It contains a DNA-dependent DNA polymerase
(E) It contains an RNA-dependent DNA polymerase

47. Which of the following statement about homocysteine is   not   true: (A) It is a homologue of cysteine, differing by addition of methylene bridge (-CH2-). (B) It is found in some proteins. (C) It is biosynthesized from methionine by the removal of its terminal Ce methyl group. (D) It can be recycled into methionine or converted into cysteine with the aid of certain B-vitamins. (E) It is a possible risk factor for coronary artery disease.

48. Considered the following saturated fatty acid, how many β-oxidation cycle does it need to completely metabolize the above fatty acid to acetyl-CoA?  (A) 2. (B) 3. (C) 4. (D) 6. (E) 12.

49. Considered the following transamination reaction in amino acid biosynthesis, what amino acid would be produced?  (A) Glu. (B) Asp. (C) Gln. (D) Thr. (E) Arg.

50. Given the saturated fatty acid shown below, how many ATPs can be produced when it is completely metabolized?  Some useful info: i. In the TCA cycle, one Acetyl-CoA gives 3 moles of NADH, 1 mole of FADH2, and 1 mole of GTP. ii. One mole of NADH produces 2.5 mole of ATP.  iii. One mole of FADH2 produces 1.5 mole of ATP. (A) 30. (B) 34. (C) 36. (D) 50. (E) 52.

複選題2. Regarding to cell cycle which statements is (are) CORRECT? (A) Cell cycle can be promoted by protein degradation (B) Kinases control key events (C) Most of the kinases involved in cell cycle are tyrosine kinases (D) CDK is the major kinase (E) G1 and G2 do not exist in bacteria

複選題3. Which abbreviations of amino acid are hydrophilic? (A) K (B) W (C) D (D) G (E) S

複選題4. Regarding to translation which statements is (are) CORRECT? (A) It requires ATP. (B) It requires GTP. (C) eIF2 binds to the CAP. (D) eIF4 binds to the 40S. (E) First codon is mainly AUG.

複選題5. About splicing, which is (are) CORRECT? (A) Trans-splicing contains an intron from other mRNA (B) Ul binds to the branch site (C) U2 binds to the 5' splicing site (D) U4/U5/U6 promote bending of intron (E) The ligation step is achieved by the transesterification reaction.

複選題6. About double strand break repair, which is (are) NOT CORRECT? (A) Ku is a single strand binding protein (B) MRE11 is a double strand binding protein (C) ATR senses double strand breaks (D) BRCA1 promotes strand transfer (E) DNA ligation is a required step

7. RNA Pol II can transcribe the following genes: (A) tRNA (B) rRNA (C) ncRNA (D) mRNA (E) Actin