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108年 - 108 國立臺灣大學_碩士班招生考試:基礎分子生物學#125746
> 試題詳解
7. RNA Pol II can transcribe the following genes:
(A) tRNA
(B) rRNA
(C) ncRNA
(D) mRNA
(E) Actin
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詳解 (共 1 筆)
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B1 · 2025/09/24
#6781116
1. 題目解析 本題的核心是了解RNA...
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8. About DNA replication, which is (are) NOT CORRECT? (A) Origins contain repetitive sequences (B) RPA is required for binding (C) DnaB opens the double strand (D) PCNA facilitates the movement of polymerase (E) Topoisomerase solves the supercoiling stress
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複選題9. Regarding to mitochondria, which is (are) CORRECT? (A) ATPase is at the intermembrane space (B) Glucose converts to pyruvate therein (C) TCA cycle occurs there (D) ATP is generated by substrate -level acetylation (E) The net change in standard free energy is positive.
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複選題10. Regarding to translation, which is (are) CORRECT? (A) Hairpin at mRNA can leading to pausing of polymerase (B) Factor binding at specific mRNA sites can block translation (C) Ribosomes contain P and A sites. (D) Bacteria mRNA contain Kozak sequence (E) 80S ribosome usually recognizes a cap.
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複選題11. Which methods can be used to detect protein-protein interaction? (A) Farwestern (B) Yeast two hybrid (C) Gel mobility shift (D) Immunofluorescence (E) Coimmunoprecipitation
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複選題12. Regarding to cell cycle, which is (are) CORRECT? (A) Cyclin D expresses at M phase (B) Separase cleavages condensin to separate 2 chromatids. (C) P21 is a stress-induced inhibitor of CDK (D) P27 expresses in G1 to keep cells in G0 (E) P53 is induced under stress to drive P27
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複選題13. Regarding to cancer, which is (are) CORRECT? (A) PD1 expression level is critical for the success of the PD1 antibody-conducted immunotherapy. (B) RB is a CDK inhibitor at G1 (C) RB binds the G1cyclin D (D) HIF1a stabilization is critical for metastasis (E) Telomerase expression is required for its maintenance
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複選題14. About mismatch repair, which is (are) CORRECT? (A) MutS binds to the methylation site (B) UvrB bends the DNA (C) UvrC cleavages the sites around the damage (D) Only one strand is repaired (E) The pathway is frequently damaged in liver cancer
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複選題15. Which methods can be used to change the expression of a wild-type gene? (A) Small interference RNA (B) Antisense RNA (C) MicroRNA (D) TALEN gene editing (E) CRISPR/Cas9 editing
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複選題16.About chromatin, which is (are) CORRECT? (A) Genes at heterochromatin is usually silent (B) Telomeric genes are highly expressed (C) Histone tails are usually highly methylated (D) H3K4 is an active mark (E) X chromosome is inactivated by a long non-coding RNA
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複選題17.About transcription, which is (are) CORRECT? (A) A transcriptional factor can bind to an enhancer which is far away from the promoter. (B) The TATA box is located at all promoters of RNA Pol II transcribed gene. (C) The TATA box is usually bound by a TATA box binding protein (D) Histone methylation opens chromatin (E) Histone acetylation opens chromatin
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