複選題11. Which of the following statements regarding "Cell and Matrix Interaction" are CORRECT? (A) Integrins are heterodimers composed of a and ẞ subunits, which is expressed in a cell-specific manner and binds to the tripeptide sequence of Arg-Gly-Asp (B) EDTA can induce the dissociation of cadherin cell-cell interactions by chelating the Ca2+ (C) The desmosomes contain integrins and associate with actin filaments on the cytoplasmic side (D) The gap junctions are protein lined channels connecting the cytoplasms of adjacent cells, which allow passage of ions and small molecules between the cells (E) Polymerization of collagen into large collagen fibers occurs in the endoplasmic reticulum