複選題

15. Which of the following is/are tumor suppressor genes.
(A) Rb
(B) Мус
(C) p21
(D) Jun
(E) EGFR

複選題11.Select the CORRECT statements. (A) Micro RNA is a small non-coding RNA. (B) Micro RNA contains 10 nucleotides. (C) Micro RNA is the small interfering RNA (siRNA). (D) Micro RNA silences RNA functions as post-transcriptional regulation. (E) RNA polymerase III transcribes some micro RNA.

複選題12.Select the FALSE statements. (A) RNA splicing can remove introns. (B) Reverse transcriptase can convert DNA to RNA. (C) The consensus for the intron donor site is AG and the acceptor site is GU. (D) Splicesome is a RNA-protein complex to remove introns. (E) Splicing can occurs in bacteria and viruses.

複選題13.Select the FALSE statements. (A) Most proteins use co-translation/translocation pathways. (B) The secretory protein contains a signal peptide. (C) The chaperon protein functions for secretory protein translocation. (D) The transmembrane G-protein coupled receptors have an amino-terminal signal sequence. (E) Most the targeting sequence of peroxisome matrix proteins is on the C-terminal extension to import them to the organelle.

複選題14.Select the CORRECT statements. (A) Mitochondria can generate the chemical energy (ATP) source for cells. (B) Mitochondria contain their own genome. (C) Mitochondria can store calcium for cell homeostasis of calcium. (D) Mitochondria process glycolysis. (E) Mitochondria cristae are derived from the folding of outer membrane.

複選題16.Select the CORRECT statements. (A) Golgi apparatus processes protein glycosylation. (B) Proteins are synthesized at Golgi and then fused with ER. (C) Trans Golgi can package proteins into vesicles destined to lysosome. (D) Antibody containing vesicles are predominant in B cells. (E) Mitochondria contain signal membrane.

複選題17.Select the FALSE statements. (A) During interphase, for chromosome segregation. (B) GO is resting phase. (C) During S phase, nuclear DNA contents are duplicated. (D) Cyclin A and Cdc2 can be used as markers for G1/S. (E) p16 is a cell proliferation marker

複選題18.Select the CORRECT statements. (A) Apoptosis is the process of programmed cell death. (B) Necrosis is the process of programmed cell death. (C) Necroptosis is the process of programmed cell death. (D) Autophagy is caspase-dependent. (E) TUNEL assay is for apoptosis detection.

複選題19.Select the CORRECT statements. (A) Epigenetic trait means the changes in DNA sequences. (B) Nucleosome is the DNA wrapped around eight histones (H2A, H2B, H3, H4) (C) Histone H3 can be methylated at serine. (D) Histone H3 can be acetylated at threonine. (E) An imbalance in the equilibrium of histone acetylation is associated with tumorigenesis and cancer progression.

複選題20. Select the FALSE statements. (A) Ligands bind to membrane receptors to activate downstream signaling. (B) Steroid hormone is a lipid-soluble molecule, and can cross the plasma membrane to reach nuclear receptor. (C) Her2/neu is a ligand and also an oncogene. (D) The mutated EGFR can constitutively activate the downstream signaling. (E) In case of Wnt signaling, beta-catenin phosphorylation is for survival.

21. Which of the following is NOT a component of a ribonucleotide? (A) Glucose (B) Ribose (C) Uracil (D) Thymine (E) Adenine