試題詳解

31. Which of the following descriptions about intracellular protein trafficking are correct?
(A) trans-Golgi network is where vesicles bud off and leave Golgi, and cis-Golgi network is where ER-derived vesicles fuse with Golgi
(B) COPII vesicles mediate antegrade transport from ER to Golgi, whereas COPI vesicles mediate retrograde transport from Golgi to ER
(C) Receptor-mediate endocytosis requires adaptor protein complex 1 (AP-1), which then recruits clathrin to form invaginated coated pits at the plasma membrane
(D) Receptor-mediated endocytosis could be blocked by inhibiting the GTPase dynamin or lowering temperature down to 4°C
(E) The SNARE complex controls vesicle docking at the target membrane, whereas Rab small GTPases control vesicle fusion with the target membrane