複選題35.CRISPR is a famous genome-editing tool. Which of following statements are TRUE:(A) CRISPR is discovered as a bacterial immune system(B) There is only one type of CRISPR(C) Two major components that introduced into mammalian cell for genome editing are cas-9 protein and guide DNA(D) Creating gene deletion using CRISPR rely on the mistake of DNA repairing system in the host cell(E) The recognition sequence for the cas-9 system are three nucleotide PAM sequence