1. 肺腫瘤的治療選項，上皮生長因子接受體(EGFR,
epidermal growth factor receptor)的小分子抑制劑藥物
是重要的選擇。下列何種病人肺腫瘤有「EGFR突
變」的機率最高?
(A) A 35-year-old woman with a carcinoid tumor
(B) A 25-year-old man with a hamartoma
(C) A 75-year-old man with squamous cell carcinoma
and a history of asbestos exposure
(D) A 58-year-old man with a 100-pack-year history of
tobacco use with small-cell lung carcinoma
(E) A 54-year-old woman who has never smoked with
an adenocarcinoma
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