18 有關非類固醇抗發炎藥物（NSAIDs）引起的胃病變敘述，下列何者正確？
(A)同時服用 aspirin 及 COX-2 抑制劑與只用 COX-2 抑制劑的腸胃出血風險相當
(B)抗血小板藥物 clopidogrel 並不會引起胃腸出血
(C)發生胃腸出血的風險為 indomethacin＞diclofenac＞ibuprofen
(D)COX-2 抑制劑可減少胃腸出血的風險，但可能增加心血管風險，而非選擇性 NSAID 則不會增加心 血管風險

答案：登入後查看
統計： A(2), B(7), C(47), D(8), E(0) #1054373

詳解 (共 2 筆)

#3937284
D:
https://meddataspeaks.wordpress.com/2015/07/17/%E8%97%A5%E7%89%A9%E5%AE%89%E5%85%A8-nsaids%E8%88%87%E5%BF%83%E8%A1%80%E7%AE%A1%E7%96%BE%E7%97%85%E9%A2%A8%E9%9A%AA%E8%AD%B0%E9%A1%8C%E7%BE%8E%E5%9C%8Bfda-2015%E8%AD%A6%E8%A8%8A%E6%9B%B4/amp/
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#6274467
(A)並用aspirin的出血風險較高
Studies of the COX-2 selective agents (COX-2 inhibitors) have demonstrated that they are associated with a significantly reduced risk for upper and lower gastrointestinal complications compared with conventional NSAIDs, although recent evidence indicates that this effect is partially or totally ameliorated in patients who are receiving concomitant aspirin.
(B)抗凝血藥物還是會
(D)NSAID也會增加心血管風險Furthermore, recent evidence suggests that at least some of the COX-2 inhibitors are associated with cardiovascular adverse effects at certain doses; fewer relevant data are available for conventional NSAIDs (generally studied many years ago), although accumulating information suggests that at least some of these also increase risk for cardiovascular events.
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