18. Which method(s) can be used to functionally inactivate a gene without changing its DNA sequence?
(A) CRISPR/Cas9 genome editing
(B) RNAi interference
(C) Site directed mutagenesis
(D) TALEN genome edditing
(E) Cre-Lox and FLP/FRT recombinase target-based gene inactivation
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