47.神經母細胞瘤(neuroblastoma)是兒童顱外最常見的實質性腫瘤,下..-阿摩線上測驗
Chris 大二下 (2020/06/02): The term neuroblastoma is commonly used to refer to a spectrum of neuroblastic tumors (including neuroblastomas, ganglioneuroblastomas, and ganglioneuromas) that arise from primitive sympathetic ganglion cells. The neuroectodermal cells that comprise neuroblastic tumors originate from the neural crest during fetal development, and are destined for the adrenal medulla and sympathetic nervous system. By contrast, pheochromocytomas and paragangliomas arise from a different type of cell, the chromaffin cell, which also migrates from the neural crest to the adrenal gland Neuroblastomas can arise anywhere throughout the sympathetic nervous system. The adrenal gland is the most common primary site (40 percent), followed by abdominal (25 percent), thoracic (15 percent), cervical (5 percent), and pelvic sympathetic ganglia (5 percent) (C)當懷疑小兒罹患神經母細胞瘤時,須收集24小時尿液檢測其中的兒苯酚氨(catecholamine)或其代謝產物 (例如:dopamine, homovanillic acid, vanillylmandelic acid),通常會發現數據上升
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