試題詳解

22. The mechanism of chymotrypsin involves which of the following elements?
(A)deprotonation of an active site Asp residue by His to start the reaction
(B) formation of an acyl-enzyme intermediate that must be hydrolyzed to complete the reaction
(C)stabilization of the positively charged His by a GIn residue
(D)direct deprotonation of water by His to generate a hydroxide ion for initiation of the reaction
(E)both a and b occur