試題詳解

33. The mechanism of chymotrypsin involves which of the following elements?
(A) deprotonation of an active site Asp residue by His to start the reaction
(B) formation of an acyl-enzyme intermediate that must be hydrolyzed to complete the reaction
(C) stabilization of the positively charged His by a Gin residue
(D) direct deprotonation of water by His to generate a hydroxide ion for initiation of the reaction
(E) both a and b occur