25. Vesicular transport describes vesicles bud off from one compartment and fuse with another. Most transport vesicles form from specialized, coated regions of membranes. They therefore bud off as coated vesicles. Which statement(s) is correct regarding coated vesicles?
(1) Clathrin-coated vesicles mediate transport originating from the Golgi apparatus, endosome, and the plasma membrane.
(2) COPI-coated vesicles contribute to the ER-to-Golgi transport, comprising large protein subcomplexes that are made of seven different protein subunits.
(3) The retromer complex has been shown to mediate retrieval of various transmembrane receptors, such as the cation- independent mannose 6-phosphate receptor.
(A) (3) only
(B) (I) and (2)
(C) (2) and (3)
(D) (1) and (3)
(E) All of above are correct.
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