28. Which of the following statements concerning matrix-assisted laser desorption ionization-time of flight-mass spectrometry (MALDI-TOF-MS) is INCORRECT?
(A) MALDI-TOF-MS commonly detects analytes as protonated, such as [M+H]⁺, rather than as bare molecular ions.
(B) Delayed extraction in MALDI-TOF-MS improves mass resolution by compensating for initial kinetic energy dispersion of the ions.
(C) MALDI-TOF-MS is well suited for the analysis of high-molecular-weight biomolecules.
(D) The matrix in MALDI serves only as an inert support and does not participate in the ionization process.
(E) In MALDI-TOF-MS, time-of-flight analysis separates ions based on their mass-to-charge ratio by measuring their flight times under a fixed accelerating potential.