28.In Watson-Crick model of double-helical DNA, how many bases form one turn of helix?

(A) 8

(B) 9

(C) 10

(D) 14

(E) 16

29.Exonuclease activity is important for DNA polymerase function because(A) It randomly removes the newly incorporated nucleotide.(B) It removes oxidized base.(C) It removes mismatched nucleotide in the exonuclease site for proofreading.(D) It removes primers present in the lagging strand during DNA replication(E) It increases DNA polymerization reaction

30. Which of the following RNA has the highest percentage of modified bases(A) mRNA(B) HnRNA(C) rRNA(D) tRNA(E) Micro-RNA

複選題31. Which of following bonds do not belong to covalent bonds:(A) disulfide bond.(B) hydrogen bond.(C) phosphodiester bond.(D) peptide bond(E) van der Waals

複選題32. Which of following statement(s) for nucleic acid is/are True: (A) C, T are Purines (B) There are two hydrogen bonds between CG pairing (C) During the process of free nucleotides becoming RNA, every single nucleotide added, two phosphate groups are released. (D) The higher the GC content, the lower the Tm value is. (E) RNA at neutral pH buffer (pH=7) has no charge

複選題33. Which of the following statements about RNA are True: (A) There are primary, secondary and tertiary structure in RNA (B) The difference between the basic unit of DNA and RNA are at 3' hydrogen atom in the ribose ring (C) RNA can function as an enzyme (D) Majority of RNAs in the cell are coded for protein sequence. (E) RNA is a highly negatively charged molecule at a neutral pH environment

複選題34. Which of following statements are TRUE:(A) Structure of nucleotides are composed of five-member ring sugar, base and phosphate group.(B) Amino acids are composed of amino group, carboxyl group and side chains(C) The bond which connects two amino acids together is called peptide bond(D) The bond which connects two nucleotides together is called glycosidic bond(E) The 1st amino acid is usually named as the 5' most amino acid

複選題35.CRISPR is a famous genome-editing tool. Which of following statements are TRUE:(A) CRISPR is discovered as a bacterial immune system(B) There is only one type of CRISPR(C) Two major components that introduced into mammalian cell for genome editing are cas-9 protein and guide DNA(D) Creating gene deletion using CRISPR rely on the mistake of DNA repairing system in the host cell(E) The recognition sequence for the cas-9 system are three nucleotide PAM sequence

複選題36. Which of the following statements are True:(A) tRNA are transcribed by RNA polymerase I(B) Pre r-RNA are transcribed by RNA polymerase II(C) mRNA are transcribed by RNA polymerase II(D) long noncoding RNA are transcribed by RNA polymerase II(E) microRNA precursors are transcribed by RNA polymerase II

複選題37. Which of the following statements for mRNA are True:(A) Prior to 5' mRNA capping, there are three phosphate at 5' end of mRNA(B) Cap structure is critical for protein translation initiation.(C) Poly( A ) tail of the mRNA is encoded in the DNA sequence(D) Maturation of intron containing pre-mRNA requires splicing process(E) RNA splicing is one of the first discovered enzymatic reaction that can be catalyzed by Ribozyme.

複選題38.For the statements of various biological processes in different cell compartments, which statements are TRUE(A) Nucleolus is located in the nucleus(B) rRNA are accumulated in the nucleolus(C) RNA synthesis takes place in the cytoplasm(D) DNA replication takes place in nucleolus(E) Mitochondria has its own DNA

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