29 Didanosine 抗 AIDS 病毒之作用，係由於在體內轉換成下述那一..-阿摩線上測驗

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29 Didanosine 抗 AIDS 病毒之作用，係由於在體內轉換成下述那一種活性物所致？
(A) 2',3'-Deoxyadenosine triphosphate
(B) 2',3'-Deoxyinosine triphosphate
(C) 2',3'-Deoxyguanosine triphosphate
(D) 2',3'-Deoxycytosine triphosphate

藥物化學與生藥學- 92 年 - 92-1 專技高考_藥師：藥物化學與生藥學#10634

答案：A
難度： 適中

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	1F Swear 幼兒園下 (2015/12/14) 檢舉
	2F pretest 高三下 (2018/01/16) Didanosine (ddI) is a nucleoside analogue of adenosine.^[7] It differs from other nucleoside analogues, because it does not have any of the regular bases, instead it has hypoxanthine attached to the sugar ring. Within the cell, ddI is phosphorylated to the active metabolite of dideoxyadenosine triphosphate, ddATP, by cellular enzymes. Like other anti-HIV nucleoside analogs, it acts as a chain terminator by incorporation and inhibits viral reverse transcriptase by competing with natural dATP... 查看完整內容 Didanosine (ddI) is a nucleoside analogue of adenosine.^[7] It differs from other nucleoside analogues, because it does not have any of the regular bases, instead it has hypoxanthine attached to the sugar ring. Within the cell, ddI is phosphorylated to the active metabolite of dideoxyadenosine triphosphate, ddATP, by cellular enzymes. Like other anti-HIV nucleoside analogs, it acts as a chain terminator by incorporation and inhibits viral reverse transcriptase by competing with natural dATP. 檢舉
	3F 菜餅大三上 (2023/03/25) Nucleoside Reverse Transcriptase Inhibitor (NRTI) Didanosine 機轉：抑制反轉錄酶(RT)。前驅藥，需磷酸化成 2 ' , 3 '-dideoxyadenosine triphosphate (ddATP)才具有活性。為 Inosine 的類似物，最終代謝為尿酸。檢舉

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29 Didanosine 抗 AIDS 病毒之作用，係由於在體內轉換成下述那一..-阿摩線上測驗

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