專技 - 藥物治療學題庫下載題庫

本來很堅定選A就結束了 但看到還有人討論其他選項 很好奇就自己查了一下
但不確定是否正確 如果有誤還請告知
uptodate:

Approximately 65 to 75 percent of cases of AKI in the hospital are due to either prerenal disease or ATN . A report from Madrid, for example, evaluated all 748 cases of AKI at 13 tertiary hospital centers . The most frequent causes were:

●ATN – 45 percent

●Prerenal disease – 21 percent

●Acute on chronic kidney failure – 13 percent (mostly due to ATN or prerenal disease)

●Urinary tract obstruction – 10 percent

●Glomerulonephritis or vasculitis – 4 percent

●Acute interstitial ...

本來很堅定選A就結束了 但看到還有人討論其他選項 很好奇就自己查了一下
但不確定是否正確 如果有誤還請告知
uptodate:

Approximately 65 to 75 percent of cases of AKI in the hospital are due to either prerenal disease or ATN . A report from Madrid, for example, evaluated all 748 cases of AKI at 13 tertiary hospital centers . The most frequent causes were:

●ATN – 45 percent

●Prerenal disease – 21 percent

●Acute on chronic kidney failure – 13 percent (mostly due to ATN or prerenal disease)

●Urinary tract obstruction – 10 percent

●Glomerulonephritis or vasculitis – 4 percent

●Acute interstitial nephritis – 2 percent

●Atheroemboli – 1 percent
由上可知腎小管壞死ATN是造成AKI的原因大宗

(A)amikacin：腎中 腎小管壞死ATN
(B)warfarin：較無和腎相關副作用
(C)diltiazem：腎前 出球小動脈舒張
(D)levofloxacin：腎中 急性間質性腎炎AIN

故選(A)，其他選項(C)(D)也對腎有損傷但(A)較佳

Ref:uptodate