36 王小姐今年 29 歲，規律服用 ethinylestradiol 30 mcg/levonorgestrel 125 mcg 及 paroxetine。因偏頭痛就醫，醫師診察後處方 sumatriptan 治療，下列敘述何者正確？
(A) Sumatriptan 與 ethinylestradiol 30 mcg/levonorgestrel 125 mcg 併用可能增加癲癇發作的風險
(B) Sumatriptan 與 ethinylestradiol 30 mcg/levonorgestrel 125 mcg 併用可能增加中風發作的風險
(C) Sumatriptan 與 paroxetine 併用可能增加 serotonin syndrome 的風險
(D) Sumatriptan 與 paroxetine 併用可能增加癲癇發作的風險

答案：登入後查看
統計： A(45), B(128), C(1449), D(81), E(0) #411547

詳解 (共 4 筆)

#2296913

Sumatriptan和避孕藥無交互作用

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0
#4065466

Sumatriptan 是 5-HT1B/1D receptors 的致效劑，主要治療偏頭痛。

Paroxetine是SSRI，阻斷血清素再吸收，增加血清素在血液中的濃度，治療憂鬱症。

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#791148
Paroxetine (also known by the trade name Paxil among others) is an antidepressant drug of the SSRI type. 
Sumatriptan :Serotonin 興奮劑
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#810415
Sumatriptan binds with high affinity to human cloned 5-HT1B/1D receptors. IMITREX presumably exerts its therapeutic effects in the treatment of migraine headache by binding to 5-HT1B/1Dreceptors located on intracranial blood vessels and sensory nerves of the trigeminal system.
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0