36. In translation clongation, which molecule binds incoming aminoacyl-tRNA for loading it to A site:
(A) EF-Tu
(B) EF-Ts
(C) EF-G
(D)myosin
(E)importin

37. A silent mutation at the protein-coding region of genome will cause: (A) protein degradation (B) early termination of protein synthesis (C) amino acid change (D)protein targeting error (E)none of above

38. Which molecule is NOT required for peptide bond formation at ribosome? (A) rRNA (B) aminoacyl-tRNA (C) ribosomal large subunit (D)ATP (E)all of above are required

39. G protein is active when: (A) GDP replaces GTP (B) It is bound by its ligand and transported to the nucleus (C) GTP is bound to it (D)It is phosphorylated by protein kinase (E) Ca2+ binds to a protein-linked receptor

40. The cholera toxin does not allow GTP to be hydrolyzed to GDP. What effects of cholera toxin would you expect to see in the cell? (A) The inactivation of ligand-gated ion channels (B) The inactivation of G-protein linked signaling pathways (C) The activated G proteins would remain locked in the "on" position, transmitting signal even in the absence of signaling molecule (D)All of the cAMP would be used up (E)All of above

41. During the transduction of a signal, one molecule or ion may be closely associated or interact with the activity of another. Select the pair that is INCORRECTLY combined. (A) Calcium–IP3 (B) cAMP–adenylyl cyclase (C) cAMP–protein kinase A (PKA) (D)PIP3–DAG (E)cGMP–Guanylyl cyclase

42. All Androgens are formed from: (A) Proteins (B) Tyrosine (C) Cholesterol (D)Small peptides (E) Fatty acid

43. Which RNA describes below is NOT non-protein coding RNA? (A) mRNA (B) IncRNA (C) tRNA (D)SiRNA (E)rRNA

44. Which description of the difference between DNA and RNA synthesis is WRONG? (A) Both of them have active and efficient proofreading function (B) Ribonucleotides are used in RNA synthesis (C) RNA polymerase does not need primer to initiate the synthesis of RNA (D)U replaces T as the complementary base for A in RNA (E) Only portions of the genome are transcribed into RNA, whereas the cntire genome must be copied, once and only once during DNA replication

45. Which modification describes below is NOT eukaryotic RNA processing? (A) 5' capping (B) Spicing (C) 3' polyadenylation (D)Phosphorylation (E)Intron removal

46. Which transcriptional step is NOT regulated by CTD (carboxy terminal domain) phosphorylation/dephosphorylation of RNA polymerase II? (A) Promoter clearance (B) Promoter elongation (C) Promoter termination (D)mRNA process (E)Promoter initiation

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