試題詳解

36. Which of the following accurately describes the role of Ran-GTP in the directionality of nuclear transport?
(A) Ran-GTP is hydrolyzed to Ran-GDP in the cytoplasm, releasing cargo from exportins.
(B) The Ran-GTP gradient, maintained by RanGEF in the nucleus and RanGAP in the cytoplasm, ensures unidirectional cargo transport.
(C) Ran-GTP directly phosphorylates nuclear transport receptors to facilitate cargo import and export.
(D) Ran-GTP binds importin in the cytoplasm to prevent premature cargo release.
(E) Ran-GTP hydrolysis occurs exclusively within the nuclear pore complex to control bidirectional movement.