(A) Doxorubicin : inhibits the progression of topoisomerase II (DNA transcription) (B) Topotecan : Topotecan is a semi-synthetic derivative of camptothecin. (Topo I) (C) Paclitaxel : paclitaxel stabilizes the microtubule polymer. This blocks the progression of mitosis (D) Bleomycin : induction of DNA strand breaks