46.有關豬水腫病，何者錯誤？
(A)好發於哺乳豬
(B)病原是大腸桿菌
(C)引起多發小動脈類纖維素變性
(D)常有神經症狀

Edema Disease(ED)水腫病
(A)ED mostly occurs during the first few weeks after weaning.好發於斷乳後數周
(C)The hallmark microscopic lesion of ED is a degenerative angiopathy affecting small arteries and arterioles 
with associated edema of surrounding tissues. In the walls of some affected vessels, fibrinoid material is deposited.主要影響小型動脈及小動脈，某些血管壁會沉積纖維素性物質。
(D)In pigs that have recovered from natural outbreaks or survived for several days following acute signs, there may 
be multifocal encephalomalacia in the brain stem together with typical lesions in the small arteries and arterioles . Malacia is thought to be due to ischemia secondary to vascular injury.看起來神經症狀比較像慢性病程才會出現，血管傷害引起腦缺血軟化，有沒有常見就不太確定
結論：edema disease E. coli (EDEC)製造毒素Stx2e，造成退化性血管疾病，增加血管通透性，可發現低蛋白水腫液於多種組織間，常見如眼瞼、前額。
(Disease of swine ,11th edition, p820-822)