48.在nonselective NSAIDs中,下列何者較無心血管方面之危險性?
(A)Ibuprofen
(B)Indomethacin
(C)Naproxen
(D)Tolmetin
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統計: A(325), B(204), C(1472), D(327), E(0) #408152
統計: A(325), B(204), C(1472), D(327), E(0) #408152
詳解 (共 3 筆)
#1408465
NSAID比較
消炎indomethacin>diclofenac>piroxicam>ketoprofen>lornoxicam>ibuprofen>ketoprolac>aspirin
腎毒性indomethacin>ibuprofen=mefenamic acid=naproxen>piroxicam>sulindac
心毒性rofecoxib>diclofenac>indomethacin>meloxicam>ibuprofen>piroxicam>naproxen
136
1
#884951
Naproxen usually sold as the sodium salt naproxen sodium is a nonsteroidal anti-inflammatory drug of the propionic acid class and is commonly used for relief of a wide variety of pain, fever, swelling and stiffness. It is the preferred NSAID for long-term use in people with a high risk of cardiovascular complications, due to its relatively low risk of causing such complications. Naproxen has an intermediate risk of causing stomach ulcers as compared with ibuprofen, which is low risk, and indometacin, which is high risk. In order to reduce the risk of stomach ulceration, it is often combined with a proton-pump inhibitor during long-term treatment, in those with pre-existing stomach ulcers, or a history of developing stomach ulcers while on NSAIDs.
14
0