49 Metoclopramide 可以促進胃腸蠕動功能以及止吐作用的主要藥理機制在於：
(A) 5HT 4 受體拮抗劑
(B) 抑制胃腸道Acetylcholinesterase 的酵素活性
(C) 是motilin 受體的致效劑
(D) 多巴胺D 2 受體拮抗劑

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統計： A(36), B(7), C(12), D(67), E(0) #672628

詳解 (共 1 筆)

#1624046

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Figure 2.

Mechanism of action of metoclopramide. (A) Metoclopramide promotes gut motility by inhibiting presynaptic and postsynaptic D2 receptors as well as presynaptic 5-HT4 receptors. (B) Metoclopramide also produces antiemetic effects by inhibition of D2 and 5-HT3 receptors in the CTZ.
CTZ: Chemoreceptor trigger zone; GI: Gastrointestinal.
Adapted from [30].

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