50.下列關於HIV(Human immunodeficiency virus)..-阿摩線上測驗
2F Chris 大二下 (2018/07/03)
The co-receptor used upon initial infection by HIV is CCR5, which is expressed on myeloid and peripheral, activated, central memory, intestinal, and other subsets of CD4 T cells (macrophages, [M]-tropic virus). Later, during chronic infection of a person, the env gene mutates so that the gp120 binds to a different chemokine receptor (CXCR4), which is expressed primarily on T cells (T-tropic virus) |
3F
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4F MORRIS M114 高一上 (2020/06/04)
POL (產生:reverse transcriptase) HIV 病毒利用 receptor-mediated endocytosis 進入細胞,使用的主要 receptor 是 CD4,co-receptor 分 成兩類, M(Macrophage)-tropic strain 是 CCR5(此 tropism 又稱 R5), T(T cell)-tropic strain 才是CXCR4(此 tropism 又稱 X4) (A) |