專技 - 藥物治療學題庫下載題庫

話說那個C

之前實習時聽過thyroid storm的報告

日本guideline反而是建議MMI > PTU

雖然只是for考試但還是附上連結供參

Regarding the long-term efficacy of ATDs in thyrotoxicosis in compensated Graves’ patients, a randomized prospective study performed in Japan revealed that MMI (30 mg/day) normalized thyroid hormone levels more rapidly than PTU (300 mg/ day). This study also showed that the incidence of adverse effects in patients treated with MMI was significantly lower than in those treated with PTU [25]. Based on these findings, the JTA guidelines recommend MMI as the first-choice ATD for the treat...

話說那個C

之前實習時聽過thyroid storm的報告

日本guideline反而是建議MMI > PTU

雖然只是for考試但還是附上連結供參

Regarding the long-term efficacy of ATDs in thyrotoxicosis in compensated Graves’ patients, a randomized prospective study performed in Japan revealed that MMI (30 mg/day) normalized thyroid hormone levels more rapidly than PTU (300 mg/ day). This study also showed that the incidence of adverse effects in patients treated with MMI was significantly lower than in those treated with PTU [25]. Based on these findings, the JTA guidelines recommend MMI as the first-choice ATD for the treatment of compensated Graves’ disease, except during early pregnancy [26]. Therefore, MMI has been favored by physicians in Japan for the treatment of compensated Graves’ disease and more frequently used to treat uncompensated thyrotoxicosis in thyroid storm in the nationwide surveys (278 out of 356 cases, 78%) [8]. In addition to the nationwide surveys in Japan, a recent study from the United States also reported no significant difference in outcomes of patients with thyroid storm treated with MMI or PTU [27]. These observations together provide supporting evidence that MMI may not be disadvantageous compared to PTU for the treatment of thyrotoxicosis in thyroid storm.